The Case for the Oxford Comma

The Oxford comma is a subject of great debate among writers. Some style guides, such as the AP Stylebook, argue that the Oxford comma is stylistic and unnecessary. Others, such as the AMA Manual of Style and The Elements of Style, argue that the Oxford comma is essential for accuracy and clarity.

What is the Oxford comma?

The Oxford (or serial) comma is the final comma in a list of things. The comma precedes the conjunction (eg, and, or) in the sentence.

I ate a sandwich, chips, and an apple for lunch.

Why should you use the Oxford comma?

Omitting the Oxford comma can lead to confusion.

Let’s look at an example.

Without the Oxford comma

This research is dedicated to my thesis committee, Susan and John.

Without the Oxford comma, a reader could interpret your sentence as your research is dedicated to your thesis committee, and your committee includes Susan and John. However, what if Susan is a research technician and John is a graduate student? Then the sentence would not be accurate.

The Oxford comma helps to ensure that the details in the sentence are accurate. And accuracy is essential in science.

With the Oxford comma

This research is dedicated to my thesis committee, Susan, and John.

Let’s look at another example.

Without the Oxford comma

Cancer is often treated with chemotherapy, immunotherapy or surgery.

Without the Oxford comma, a reader could interpret the sentence as immunotherapy and surgery are types of chemotherapy. This phrasing would be inaccurate.

With the Oxford comma

Cancer is often treated with chemotherapy, immunotherapy, or surgery.

These examples might seem trivial, but major battles have occurred because of a missing Oxford comma. In 2018, truck drivers in Maine won a $5 million legal settlement thanks to an Oxford comma that was omitted from their contract.

What’s the bottom line?

Clarity and accuracy are key in scientific and medical writing. For the small price of one character, you can make your sentence more accurate and clearer for readers.


Want free tools and templates to help you enhance your scientific and medical writing? Get access to our free writing toolkit!


Crystal Herron, PhD, ELS

Crystal is an editor, educator, coach, and speaker who helps scientists and clinicians communicate with clear, concise, and compelling writing. You can follow her on LinkedIn.

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